The Best Products for Pain Management
CBD is one of several cannabinoids that are naturally present in the cannabis plant.
There are a vast range of CBD products, including oils, tinctures, balms, and candy, all of which may help people who are experiencing physical pain.
In this article, we discuss how CBD products may help relieve chronic pain. We also provide a list of potentially effective CBD products that have undergone extensive third-party testing for safety.
Cannabidiol (CBD) has gained popularity as a promising complementary remedy for various health issues, including anxiety, epilepsy, and pain management.
Is CBD effective in pain management?
CBD and other cannabinoids act on cannabinoid receptors found throughout the body. These receptors, combined with naturally occurring cannabinoids, make up the endocannabinoid system (ECS).
The ECS consists of complex cell signaling pathways in the central nervous system and immune system.
There are endogenous and exogenous cannabinoids. Endogenous cannabinoids are naturally occurring lipids that the body produces. Two of the most well-known endogenous cannabinoids are anandamide (AEA) and 2-arachidonoylglycerol.
The body does not produce exogenous cannabinoids. These compounds are part of the cannabis plant. Examples of exogenous cannabinoids include:
Cannabinoids, both endogenous and exogenous, bind to endocannabinoid receptors attached to cells. These include cannabinoid 1 and cannabinoid 2 receptors. This binding action stimulates different cell responses that influence pain signaling pathways.
CBD does not bind very well to endocannabinoid receptors. However, it may interact with neurological receptors in the spinal cord that suppress chronic inflammatory pain, as one study on mice found. CBD may also strengthen the effects of AEA, an endogenous cannabinoid that reduces pain.
According to a small 2018 study, researchers evaluated CBD’s pain-relieving effects in seven people who experienced chronic pain after having kidney transplants.
Six of the seven participants reported improvements in pain. One of the participants experienced more pain at higher CBD doses but achieved the best pain control at lower CBD doses.
In a 2015 animal study, researchers found that topical CBD reduced arthritis-related joint swelling and pain in mice. According to the authors, effective doses ranged from 6.2 to 62 milligrams (mg) per day.
While these preliminary studies suggest that CBD may help manage pain, scientists need to investigate these findings in large-scale, high-quality clinical trials.